Dab tsi yog lub luag haujlwm ntawm LED diodes hauv cov cuab yeej kho tawv nqaij?

Ib, Technical txoj cai: Molecular dialogue ntawm lub teeb thiab hlwb
LED diodes emit ib lub teeb wavelength los ntawm semiconductor cov ntaub ntawv nyob rau hauv qhov kev txiav txim ntawm ib tug sab nraud hluav taws xob teb, nrog ib tug ntau yam ntawm lub zog uas npog lub teeb pom kev (400{1}}700nm) thiab ze-infrared teeb (700-1000nm). Qhov sib txawv wavelengths nkag mus rau ntawm daim tawv nqaij mus rau qhov sib txawv qhov tob thiab tuaj yeem tsom cov qauv ntawm tes sib txawv

Lub teeb xiav (415-465nm): nkag mus rau qhov tob ntawm li 0.5mm thiab ua raws li cov hauv paus plaub hau thiab cov qog sebaceous. Los ntawm stimulating endogenous porphyrins los tsim singlet oxygen, nws tua Propionibacterium acnes thaum inhibiting sebaceous gland kev ua si thiab txo cov roj secretion.
Lub teeb liab (625-660nm): nkag mus rau qhov tob ntawm 2-3 hli, ncaj qha mus txog txheej dermis, txhawb nqa mitochondria los tsim ATP, txhawb nqa fibroblast proliferation thiab collagen synthesis, accelerates o thiab kho qhov txhab.
Lub teeb daj (585-590nm): Kev nkag mus ntawm qhov tob ntawm 0.5-2mm, nws txhim kho capillary dilation los ntawm inhibiting qhov tso tawm ntawm vascular endothelial kev loj hlob yam (VEGF), thaum tswj cov paracrine teeb liab ntawm keratinocytes thiab inhibiting melanin synthesis.
Nyob ze ntawm lub teeb infrared (830-850nm): nkag mus rau qhov tob ntawm 5-10mm, ua kom cov cellular autophagy txoj hauv kev, txhawb kev kho cov ntaub so ntswg sib sib zog nqus, thiab inhibits kev tso tawm ntawm cov kab mob.
Qhov no "wavelength phiaj" meej txuam mechanism enables LED kho cov cuab yeej los xaiv qhov pom lub teeb tsis raws li cov teeb meem ntawm daim tawv nqaij sib txawv, ua tiav kev kho tus kheej.

2, Clinical daim ntawv thov: npog tag nrho lub voj voog ntawm kev tswj ntawm daim tawv nqaij
1. Kev kho pob txuv: los ntawm kev tiv thaiv kab mob mus rau kev tiv thaiv caws pliav
Qhov "dual wavelength therapy" sib txuas lub teeb xiav (415nm) nrog lub teeb liab (630nm) tau dhau los ua tus qauv kub rau kev kho pob txuv. Lub teeb xiav tua Propionibacterium pob txuv los ntawm cov nyhuv photodynamic, thaum lub teeb liab inhibits kev tso tawm ntawm cov kab mob inflammatory thiab txhawb kev kho cov ntaub so ntswg. Cov ntaub ntawv kho mob qhia tau hais tias kev kho LED peb zaug hauv ib lub lis piam rau plaub lub lis piam tuaj yeem txo cov kab mob ntawm daim tawv nqaij los ntawm 68% thiab cov tawv nqaij uas tsis yog inflammatory los ntawm 53%, thiab tus nqi rov qab yog txo los ntawm 42% piv rau cov tshuaj ib txwm siv. Rau cov pob txuv nruab nrab mus rau qhov hnyav, kev kho mob photodynamic (PDT) siv LED ua ke nrog 5-aminolevulinic acid (ALA) tuaj yeem txhim kho qhov ua tau zoo thiab ua tiav qhov kev tshem tawm qhov mob ntawm ntau dua 90%.

2. Anti laus kho: los ntawm collagen regeneration rau photoaging reversal
Lub teeb liab (630nm) thiab ze rau - lub teeb infrared (830nm) txhawb nqa kev qhia ntawm cov noob xws li TGF - 1 thiab COL1A1, txhawb nqa cov synthesis ntawm collagen thiab elastin, nce daim tawv nqaij tuab ntawm 15% -20%, thiab txo qhov tob ntawm wrinkles los ntawm 25% -30%. Rau kev yees duab ntawm daim tawv nqaij, LED kev kho mob tuaj yeem kho UV cuam tshuam DNA kev puas tsuaj, txo cov kev ua haujlwm ntawm matrix metalloproteinase (MMP), thiab kho cov tawv nqaij elasticity. Tsis tas li ntawd, Huangguang (590nm) inhibits AKT / PI3K / mTOR txoj hauv kev, txo cov vascular dysplasia, thiab txhim kho lub ntsej muag flushing thiab capillary dilation.

3. Pigmented kab mob: los ntawm melanin inhibition mus rau vascular regulation
Rau cov kab mob pigmentary xws li melasma, 585nm daj lub teeb induces autophagy hauv melanocytes thiab tswj qhov tso tawm ntawm H19 / miR-675 axis los ntawm keratinocytes, inhibiting melanin synthesis. Cov kev tshawb fawb soj ntsuam tau pom tias nws qhov kev ua tau zoo yog piv rau qis -zog Q-hloov 1064nm laser, tab sis qhov tsis zoo tshwm sim yog txo los ntawm 60%. Rau cov kab mob vascular xws li rosacea, 590nm daj lub teeb tuaj yeem inhibit endothelial cell migration thiab VEGF secretion, ua rau 40% txo qis hauv erythema Performance index thiab tsis muaj kev pheej hmoo ntawm purpura tom qab kho laser.

4. Kev kho mob: los ntawm kev tswj kev mob mus rau cov ntaub so ntswg rov ua dua
Lub teeb liab (630nm) thiab ze rau - lub teeb infrared (830nm) tuaj yeem txo lub sijhawm kho mob ntawm cov qhov txhab mob xws li mob ntshav qab zib ko taw rwj thiab mob siab los ntawm kev txhawb nqa lub polarization ntawm macrophages, ua kom cov angiogenesis thiab cov hlab ntsha rov qab los. Tsiaj thwmsim tau pom tias kev kho LED tuaj yeem nce tus nqi ntawm qhov txhab txo qis los ntawm 35%, nce collagen deposition los ntawm 50%, thiab txo qhov caws pliav los ntawm 20%.

3, Innovation breakthrough: los ntawm cov cuab yeej optimization mus rau kev kho upgrade
1. Multi wavelength kev sib koom tes kev kho mob
Cov cuab yeej siv kho mob LED niaj hnub ua ke nrog ntau lub teeb lub teeb xws li liab, xiav, daj, thiab ze rau -infrared kom ua tiav "ib- nres" kev tswj ntawm daim tawv nqaij. Piv txwv li, qee yam khoom siv tau txais kev hloov kho dynamic spectral, uas tuaj yeem hloov qhov sib txuas ua ke raws li cov tawv nqaij: lub teeb xiav (415nm) yog siv rau kev kho pob txuv, ntxiv los ntawm lub teeb liab (630nm) rau kev tiv thaiv - lub hom phiaj inflammatory; Thaum lub sij hawm los tiv thaiv - kev laus kev kho mob, lub teeb liab (630nm) thiab nyob ze - lub teeb infrared (830nm) synergistically txhawb collagen regeneration.

2. Ntse zog tswj qhov system
Los ntawm kev saib xyuas ntawm daim tawv nqaij kub thiab lub teeb pom kev siv lub sijhawm tiag tiag, LED cov cuab yeej tuaj yeem hloov kho lub zog tso zis kom tsis txhob muaj kev pheej hmoo ntawm kev puas tsuaj thermal. Piv txwv li, hom tshiab ntawm cov cuab yeej siv lub kaw lus - lub voj kev tawm tswv yim uas yuav txo tau lub zog ceev thaum daim tawv nqaij kub siab tshaj 42 degree, ua kom muaj kev nyab xeeb kev kho mob.

3. Kev nrov hauv tsev - cov khoom siv kho mob
Nrog rau kev txhim kho ntawm micro LED chips thiab qis- lub zog tsav tsheb, cov cuab yeej siv hauv tsev LED kho tau ua tiav lub zog ceev (Ntau dua lossis sib npaug li 50mW / cm ²) thiab tswj lub wavelength meej (Δλ Tsawg dua lossis sib npaug rau 5nm). Clinical validation qhia tau hais tias qhov kev kho mob ntawm cov cuab yeej siv hauv tsev, uas yog siv 5 zaug hauv ib lub lis piam rau 15 feeb txhua zaus, piv rau cov cuab yeej kho mob, thiab cov neeg mob ua raws li cov neeg mob tau zoo dua los ntawm 70%.